I think I'll throw in my two cents. This choice totally depends on your personality. Are you a person that hates the drive and just wants to get it over with or do you enjoy travelling and seeing new places? Keep in mind, traffic will be insanely busy on the interstates this weekend. The route thru Pittsburgh seems pretty far out of the way. Rt.15 thru PA and MD is actually mostly 4 lane now after several years of improvements but there are still some very congested sections. Unfortunately the VA section is usually very bad on weekends so if you go this way you should consider I-270 from Frederick, MD to DC. I was on I-81, I-83, I-695, and I-95 from about 35 miles above Harrisburg, PA down to the south side of Baltimore in the last couple of days and can report no major construction projects to delay you on that stretch of highway. Either way, its still a long drive.